Fibromyalgia is described as a debilitating condition, characterized by extensive muscular pain and fatigue. Vitamin D is increasingly studied because it is essential for overall health, with ubiquitous involvement in various inflammatory and pain pathways. Little is known about vitamin D's role in fibromyalgia.
Evidence from clinical research highlight an association between vitamin D deficiency and fibromyalgia.
There is some data that indicate "vitamin D replacement therapy may improve the quality of life in patients with fibromyalgia."
A 2020 survey of patients further demonstrated that Hypovitaminosis (serum vitamin D <25 ng/mL) may be a risk factor for worse symptom severity, anxiety, and depression in fibromyalgia patients.
Further research is required.